Evaluation of Toluidine Blue-Mediated Photodynamic Therapy for Experimental Bacterial Keratitis in Rabbits
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چکیده
منابع مشابه
Toluidine blue-mediated photodynamic effects on staphylococcal biofilms.
Staphylococci are important causes of nosocomial and medical-device-related infections. Their virulence is attributed to the elaboration of biofilms that protect the organisms from immune system clearance and to increased resistance to phagocytosis and antibiotics. Photodynamic treatment (PDT) has been proposed as an alternative approach for the inactivation of bacteria in biofilms. In this stu...
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The increased resistance of Candida albicans to antibiotic therapy indicates the need for alternative treatments for oral candidiasis. Photodynamic therapy (PDT) has been researched as an alternative tool to inactivate pathogenic microorganisms. It uses a combination of a photosensitizer and a visible light source. This study evaluated the susceptibility of C. albicans to PDT and compared the e...
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Vibrio vulnificus is a gram-negative, highly invasive bacterium responsible for human opportunistic infections. We studied the antibacterial effects of toluidine blue O (TBO)-mediated photodynamic therapy (PDT) for V. vulnificus wound infections in mice. Fifty-three percent (10 of 19) of mice treated with 100 microg of TBO per ml and exposed to broad-spectrum red light (150 J/cm(2) at 80 mW/cm(...
متن کاملExperimental Lysostaphin therapy in methicillin resistant Staphylococcus aureus induced keratitis in Rabbits: A comparative evaluation
Objective: A comparative evaluation of topical lysostaphin therapy with vancomycin and azithromycin in methicillin-resistant Staphylococcus aureus (MRSA) keratitis in a rabbit model. Methods: This study was conducted on 18 eyes of 18 rabbits. All rabbits were divided into 3 groups with 6 rabbits each. Right eyes were experimental eyes. Keratitis was induced by aseptically injecting the corneal ...
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Root canal disinfection is one of the main factors governing success of endodontic therapy. Antimicrobial photodynamic therapy (aPDT) is presented as a promising antimicrobial therapy that can eliminate microbiota present in infected root canal systems. In this study, a series of experiments investigated the effects of aPDT on cell viability and biofilm degradation ability of endopathogenic mic...
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ژورنال
عنوان ژورنال: Translational Vision Science & Technology
سال: 2020
ISSN: 2164-2591
DOI: 10.1167/tvst.9.3.13